Fructose-in-solution consumption puts on fatty tissue

ScienceDaily - Research May Provide New Link Between Soft Drinks And Weight Gain

A study done by adding fructose to the water of mice revealed that while they actually consumed fewer calories than the relevant control groups, they gained much more weight, and had 90% more body fat than the control groups.  The theory is that fructose doesn't 'trigger' mechanisms that control food intake and metabolism.  Importantly, these findings are consistent with other studies that showed that fructose and high-fructose corn syrup had negligible effects on human appetite.